1. Phase I Dose-Escalation Trial of Trametes Versicolor in Women with Breast Cancer
نویسندگان
چکیده
Introduction: Trametes versicolor, also known as Coriolus versicolor and commonly called Turkey Tail, is a medicinal mushroom hypothesized to improve immune function in women with breast cancer who have received standard treatment with surgery, chemotherapy and radiotherapy. Natural killer (NK) cell activity of peripheral blood lymphocytes in cancer patients has been associated with favorable prognosis following primary cancer treatment. Our group has previously shown that radiotherapy produces immune defects in breast cancer patients, especially in NK cell activity, an important component of the innate immune system.
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Phase 1 Clinical Trial of Trametes versicolor in Women with Breast Cancer
Introduction. Orally administered preparations from the Trametes versicolor (Tv) mushroom have been hypothesized to improve immune response in women with breast cancer after standard chemotherapy and radiotherapy. Methods. A phase I, two-center, dose escalation study was done to determine the maximum tolerated dose of a Tv preparation when taken daily in divided doses for 6 weeks after recent c...
متن کاملTrametes versicolor (Turkey Tail Mushrooms) and the Treatment of Breast Cancer
Case report “PS,” an 83-year-old woman, was diagnosed in June 2009 with advanced, metastatic inflammatory breast cancer. At the same time, she began chemotherapy with Taxol and Herceptin, she also began taking capsules of turkey tail mushroom daily. The dose was 4 g twice daily (Host Defense Turkey Tail capsules, Fungi Perfecti Laboratories, Kamilche Point, Washington). The turkey tail capsules...
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